WuXi XDC offers comprehensive and integrated discovery, CMC development and cGMP manufacturing for chemical payloads and linkers
WuXi XDC offers comprehensive and integrated discovery, CMC development and cGMP manufacturing of the payload, linkers and payload-linker chemical intermediates used in the production of Antibody Drug Conjugates (ADCs) and other bioconjugates.
WuXi XDC payload-linker R&D and GMP manufacturing is located in the newly developed area north of Changzhou in the Jiangsu Province of China, approximately 180 km from Shanghai. Beyond the extensive experience in the discovery, development, analysis and production of small molecules and payload chemical entities, the site also has strong capabilities in technologies such as catalytic hydrogenation, fluid dynamic chemistry, and biocatalysis making it a unique single-source for chemical payload-linker development and synthesis.
With a highly-vetted, and global regulatory agency approved, quality management system and cutting-edge equipment, this site is able to handle OEB-5 materials (OEL~10 ng/m3) ranging from several milligrams to tens of kilograms. The quality systems at this site satisfy the quality and cGMP standards outlined by the U.S. FDA, EMA and NMPA.
