Primary Use
Drug Substance/Drug Product
GMP-compliant production
Formulation and analytical development
QC release and stability testing
Capacity
Conjugation Drug Substance Production (“XBCM”) and Antibody Intermediates Production (“XmAb”)
XBCM1 facility with single-use reactor systems ranging from 5 liters to 500 liters and the redesigned reactor system with additional DS capacity, commenced operation in the first half of 2025.
The dual function XmAb/XBCM2 (“XBCM2 Line 1”) facility is designed with capacities ranging from 50 liters to 2,000 liters per batch for monoclonal antibody intermediates or 2,000 liters of drug substance per batch. A second line (“XBCM2 Line 2”), also with dual function design, commenced operation in November 2024.
Conjugation Drug Product Production (“XDP”)
XDP1 facility is designed to produce three million doses of bioconjugates per year in liquid or lyophilized form (3 million vials, lyophilizer 1×5 m2 & 1×20 m2 ).
XDP2 facility is designed to produce five million doses of bioconjugate drug products per year in liquid or lyophilized form (5 million vials, lyophilizer 1×5 m2 & 2×20 m2 ).
XDP3 facility i s designed t o produce seven million doses of bioconjugate drug products per year in liquid or lyophilized form (7 million vials, lyophilizer 2×30 m2 ).
XDP5 facility i s designed to produce twelve million doses of bioconjugate drug products per year in liquid or lyophilized form (12 million vials, lyophilizer 4×30 m2 ) and is expected to commence operation in 2027.
Payload Linker (“XPLM”)
XPLM1 facility is designed as a kilogram-scale payload and linker production line.